ICMT Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18983-1-AP

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Freight/Packing

Con: 203 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
isoprenylcysteine carboxyl methyltransferase

Calculated molecular weight:
32 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ICMT

Synonyms
HSTE14, ICMT, MST098, MSTP098, PCCMT, PCMT, PPMT
Background

ICMT, also named as PCCMT and PPMT, belongs to the isoprenylcysteine O-methyltransferase family. ICMT is the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. It localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. It is ubiquitously expressed. It expressed at higher levels in the cerebellum and putamen than in other brain regions and abundant expression seen in the Purkinje cells and pontine neurons.


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