IL21R Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10533-1-AP

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Freight/Packing

Con: 55 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
Raji cells, COLO 320 cells, K-562 cells, mouse thymus tissue

Positive IP detected in:
COLO 320 cells

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
COLO 320 cells

Positive FC detected in:
K-562 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:10-1:100
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 21 receptor

Calculated molecular weight:
59.1 kDa

Observed molecular weight:
68-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL21R

Synonyms
CD360, IL 21 receptor, IL 21R, IL21R, interleukin 21 receptor, NILR, Novel interleukin receptor
Background

IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.


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