IL21R Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66319-1-Ig |CloneNo.: 1D1C2

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Con: 225 μg/150 μl

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Species specificity:
human

Positive WB detected in:
K-562 cells, Jurkat cells

Positive IHC detected in:
human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:50-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 21 receptor

Calculated molecular weight:
59.1 kDa

Observed molecular weight:
65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL21R

Synonyms
CD360, IL 21 receptor, IL 21R, IL21R, interleukin 21 receptor, NILR, Novel interleukin receptor
Background

IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.


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