IRF4 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66451-1-Ig |CloneNo.: 1A12D5

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 150 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, pig, rat

Positive WB detected in:
human spleen tissue,pig spleen tissue

Positive IHC detected in:
human tonsillitis

Recommended dilution:
WB : 1:500-1:2000
IHC :

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interferon regulatory factor 4

Calculated molecular weight:
52 kDa

Observed molecular weight:
50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IRF4

Synonyms
interferon regulatory factor 4, IRF 4, IRF4, LSIRF, Multiple myeloma oncogene 1, MUM1, NF EM5
Background

Interferon regulatory factor 4 (IRF4) is a member of the IRF family of transcription factors, expressed in most cell types of the immune system. IRF4 is a transcription factor essential for the development of T helper-2 (Th2) cells, IL17-producing Th17 cells, and IL9-producing Th9 cells, as well as dendritic cell (DC). It binds to and activates the interferon-stimulated response element (ISRE) of the MHC class I promoter, and may have a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.


Back
to top