IRF5 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60088-1-Ig |CloneNo.: 2A10C5

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Freight/Packing

Con: 75 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, HepG2 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human tonsillitis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interferon regulatory factor 5

Calculated molecular weight:
56 kDa

Observed molecular weight:
63+110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IRF5

Synonyms
interferon regulatory factor 5, IRF 5, IRF5, SLEB10
Background

IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10).


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