ITGA6X1B Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 20232-1-AP

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Freight/Packing

Con: 50 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, mouse kidney tissue

Recommended dilution:
WB : 1:500-1:3000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
integrin, alpha 6

Calculated molecular weight:
127 kDa

Observed molecular weight:
62 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ITGA6

Synonyms
Background

ITGA6, also named asITGA6B, CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. This antibody is specific to isoform Alpha-6X1X2B, isoform Alpha-6X1B and isoform Alpha-6X2B.


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