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Integrin Beta 6 Polyclonal antibody

Integrin Beta 6 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 21703-1-AP

Synonyms

Integrin beta 6, integrin, beta 6, ITGB6

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using Integrin Beta 6 Polyclonal antibody (21703-1-AP)

    IHC staining of human pancreas cancer using 21703-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 21703-1-AP (Integrin beta-6 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using Integrin Beta 6 Polyclonal antibody (21703-1-AP)

    IHC staining of human pancreas cancer using 21703-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 21703-1-AP (Integrin beta-6 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using Integrin Beta 6 Polyclonal antibody (21703-1-AP)

    IHC staining of human ovary tumor using 21703-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21703-1-AP (Integrin beta-6 Antibody) at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using Integrin Beta 6 Polyclonal antibody (21703-1-AP)

    IHC staining of human ovary tumor using 21703-1-AP

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21703-1-AP (Integrin beta-6 Antibody) at dilution of 1:200 (under 40x lens).

Tested Applications

Positive IHC detected inhuman pancreas cancer tissue, human ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

21703-1-AP targets Integrin Beta 6 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Integrin Beta 6 fusion protein Ag16319
Full Name integrin, beta 6
Calculated Molecular Weight 788 aa, 86 kDa
GenBank Accession NumberBC121178
Gene Symbol ITGB6
Gene ID (NCBI) 3694
RRIDAB_2878906
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ITGB6 belongs to the integrin beta chain family. ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.

Protocols

Product Specific Protocols
IHC protocol for Integrin Beta 6 antibody 21703-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols