KLF5 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 21017-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, A549 cells, HeLa cells, HT-1080 cells, human testis tissue, mouse colon tissue, mouse small intestine tissue, PC-3 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
mouse embryo tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Kruppel-like factor 5 (intestinal)

Calculated molecular weight:
457aa,51 kDa

Observed molecular weight:
51-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KLF5

Synonyms
BTE binding protein 2, BTEB2, CKLF, Colon krueppel like factor, GC box binding protein 2, IKLF, KLF5, Krueppel like factor 5, Transcription factor BTEB2
Background

KLF5, also known as BTEB2 and IKLF, is a member of the Krueppel-like transcription factor family. It is a transcription factor for SMemb/non-muscle myosin heavy chain-B (NMHC-B). It is a molecular marker of phenotypically modulated smooth-muscle cells. KLF5 seems to be a key element linking external stress and cardiovascular remodeling. This antibody detects the 50-60 kDa isoform 1 of KLF5. The antibody can recognize isoform 2 (33 kDa) and isoform 3 (18 kDa) too.


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