KLRG1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10974-1-AP

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Con: 35 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human blood tissue, Human peripheral blood leukocyte

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
killer cell lectin-like receptor subfamily G, member 1

Calculated molecular weight:
22 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KLRG1

Synonyms
2F1, CLEC15A, KLRG1, MAFA, MAFA 2F1, MAFA L, MAFA LIKE, MAFA like receptor, MAFAL
Background

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).


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