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Anti-Mouse KLRG1 (2F1)

KLRG1 Monoclonal Antibody for FC

Host / Isotype

Golden Syrian Hamster / IgG

Reactivity

Mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

2F1

Cat no : 65084-1-Ig

Synonyms

2F1 Ag, Klrg1, MAFA, MAFA L

Validation Data Gallery

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  • Flow cytometry (FC) experiment of mouse splenocytes using Anti-Mouse KLRG1 (2F1) (65084-1-Ig)

    FC experiment of mouse splenocytes using 65084-1-Ig

    1X10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse KLRG1 (65084-1-Ig, Clone: 2F1) and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (green), or stained with 0.5 ug Golden Syrian Hamster IgG isotype control and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (black). Cells were not fixed.

Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

65084-1-Ig targets KLRG1 in FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Host / Isotype Golden Syrian Hamster / IgG
Class Monoclonal
Type Antibody
Immunogen N/A
Full Name killer cell lectin-like receptor subfamily G, member 1
GenBank Accession NumberBC101953
Gene Symbol Klrg1
Gene ID (NCBI) 50928
RRIDAB_2918387
Conjugate Unconjugated
Form Liquid
Purification MethodAffinity purification
Storage Buffer Phosphate based buffer with 0.09% sodium azide, pH 7.2.
Storage ConditionsStore at 2-8°C.

Background Information

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).

Protocols

Product Specific Protocols
FC protocol for KLRG1 antibody 65084-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols