Cytokeratin 18 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66187-1-Ig |CloneNo.: 1G11C4

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Freight/Packing

Con: 130 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells, K-562 cells

Positive IHC detected in:
human kidney tissue, human lung cancer tissue, human colon cancer tissue, human liver cancer tissue, human renal cell carcinoma tissue

Positive IF detected in:
HeLa cells, HepG2 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:600-1:2000
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 18

Calculated molecular weight:
48 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT18

Synonyms
CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.


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