LAMA4 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 10465-1-AP

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Con: 22 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human heart tissue, human heart tissue, human skeletal muscle tissue

Positive IHC detected in:
human ovary tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
laminin, alpha 4

Calculated molecular weight:
13 kDa

Observed molecular weight:
11-13 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LAMA4

Synonyms
DKFZp686D23145, LAMA3, LAMA4, LAMA4* 1, Laminin 14 subunit alpha, Laminin 8 subunit alpha, Laminin 9 subunit alpha, Laminin subunit alpha 4, laminin, alpha 4
Background

Laminin is a basement membrane glycoprotein composed of three nonidentical chains, A, B1, and B2 (PMID: 7959779). LAMA4 (laminin, alpha 4), an A chain variant, is a subunit of laminin-8 (laminin-411), laminin-9 (laminin-421) and laminin-14 (laminin-423) (PMID: 10842354; 10964957). LAMA4 is widely distributed in developing and adult human tissues, and mainly localized to mesenchyme-derived tissues (PMID: 12133914). It may have a role in formation and function of endothelium, transmigration of inflammatory cells through endothelium, and invasion of certain tumors (PMID: 17533363).


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