LYN Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18135-1-AP

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Freight/Packing

Con: 59 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
HeLa cells, HL-60 cells, Jurkat cells, K-562 cells, L02 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human kidney tissue, human hepatocirrhosis tissue, human kidney tissue

Positive IF detected in:
HeLa cells

Positive FC detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

Calculated molecular weight:
512aa,59 kDa

Observed molecular weight:
53-56 kDa,66-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LYN

Synonyms
FLJ26625, JTK8, LYN, Tyrosine protein kinase Lyn
Background

LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.


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