LYN Monoclonal antibody

LYN Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 65038-1-Ig

Synonyms

JTK8, LYN, Tyrosine protein kinase Lyn



Tested Applications

Positive WB detected inHL60 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

65038-1-Ig targets LYN in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen Recombinant Protein
Full Name v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Calculated Molecular Weight 512 aa, 59 kDa
Observed Molecular Weight 56 kDa
GenBank Accession NumberBC075002
Gene Symbol LYN
Gene ID (NCBI) 4067
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at 2-8°C. 20ul sizes contain 0.1% BSA.

Background Information

LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.

Publications

SpeciesApplicationTitle
humanWB

PLoS One

Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome.

Authors - Rajan Prabhakar P