LYN Monoclonal antibody
LYN Monoclonal Antibody for WB,ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 65038-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HL60 cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
WB | See 1 publications below |
Product Information
65038-1-Ig targets LYN in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Cited Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | Recombinant Protein |
Full Name | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
Calculated Molecular Weight | 512 aa, 59 kDa |
Observed Molecular Weight | 56 kDa |
GenBank Accession Number | BC075002 |
Gene Symbol | LYN |
Gene ID (NCBI) | 4067 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at 2-8°C. 20ul sizes contain 0.1% BSA. |
Background Information
LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.
Publications
Species | Application | Title |
---|---|---|
PLoS One Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome. |