MAP4K1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23950-1-AP

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Raji cells, Jurkat cells

Positive IP detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase kinase kinase kinase 1

Calculated molecular weight:
833aa,91 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAP4K1

Synonyms
HPK1, MAP4K1, MEK kinase kinase 1, MEKKK 1
Background

MAP4K1(Mitogen-activated protein kinase kinase kinase kinase 1) is also named as MEKKK 1, HPK1 and belongs to the protein kinase superfamily. It may function as a novel tumor suppressor and its loss plays a critical role in pancreatic cancer. MAP4K1 regulates stress responses, proliferation, and apoptosis in hematopoietic cells. This protein has 2 isoforms produced by alternative splicing.


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