MIER3 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 17543-1-AP

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Freight/Packing

Con: 27 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse uterus tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mesoderm induction early response 1, family member 3

Calculated molecular weight:
522aa,59 kDa

Observed molecular weight:
55kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MIER3

Synonyms
MIER3, FLJ35954, DKFZp781I1119, DKFZp781G1119, Mi er3
Background

The mesoderm induction early response (MIER) protein family is known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, MIER proteins may have a pivotal role in FGF-regulated cellular activities, indicating a potential influence in the progression of certain cancers [PMID:15117948]. MIER3 localizes to the nucleus and primarily functions as a transcriptional repressor. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. MIER3 is a candidate Mcs1b gene [PMID:22993404].


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