MME,CD10 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60034-2-Ig |CloneNo.: 1E7A11

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Con: 150 μg/150 μl

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Tested Applications

Applications:
ELISA, IHC
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Species specificity:
human

Positive IHC detected in:
human kidney tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Caprylic Acid/Ammonium Sulfate Precipitation

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
membrane metallo-endopeptidase

Calculated molecular weight:
750aa,86 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MME

Synonyms
Atriopeptidase, CALLA, CD10, DKFZp686O16152, Enkephalinase, EPN, membrane metallo endopeptidase, MME, NEP, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11
Background

MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).


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