MME,CD10 Monoclonal antibody
MME,CD10 Monoclonal Antibody for IHC,ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
IHC,ELISA
Conjugate
Unconjugated
CloneNo.
2F12C1
Cat no : 60034-4-Ig
Synonyms
Validation Data Gallery
Tested Applications
| Positive IHC detected in | human kidney tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
60034-4-Ig targets MME,CD10 in IHC,ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | MME,CD10 fusion protein Ag0427 |
| Full Name | membrane metallo-endopeptidase |
| Calculated Molecular Weight | 750 aa, 86 kDa |
| GenBank Accession Number | BC101658 |
| Gene Symbol | MME |
| Gene ID (NCBI) | 4311 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Caprylic Acid/Ammonium Sulfate Precipitation |
| Storage Buffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).
