MME,CD10 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60034-4-Ig |CloneNo.: 2F12C1

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Freight/Packing

Con: 150 μg/150 μl

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Tested Applications

Applications:
IHC, ELISA
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Species specificity:
human

Positive IHC detected in:
human kidney tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Caprylic Acid/Ammonium Sulfate Precipitation

Isotype:
IgG2b

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
membrane metallo-endopeptidase

Calculated molecular weight:
750aa,86 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MME

Synonyms
Background

MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).


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