MSH2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60161-1-Ig |CloneNo.: 2H5F5

Featured Product KD/KO validated

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Colo320 cells,HeLa cells, A2780 cells

Positive IHC detected in:
human colon cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)

Calculated molecular weight:
105 kDa

Observed molecular weight:
105 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MSH2

Synonyms
COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2
Background

MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell.


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