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NCOR2 Polyclonal antibody

NCOR2 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 20017-1-AP

Synonyms

CTG repeat protein 26, CTG26, N CoR2, NCOR2, Nuclear receptor corepressor 2, SMAP270, SMRT, SMRTE, SMRTE tau, T3 receptor associating factor, TNRC14, TRAC, TRAC 1, TRAC1

Validation Data Gallery

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  • Western Blot (WB) analysis of HeLa cells using NCOR2 Polyclonal antibody (20017-1-AP)

    WB analysis of HeLa using 20017-1-AP

    HeLa cells were subjected to SDS PAGE followed by western blot with 20017-1-AP (NCOR2 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of Jurkat cells using NCOR2 Polyclonal antibody (20017-1-AP)

    WB analysis of Jurkat using 20017-1-AP

    Jurkat cells were subjected to SDS PAGE followed by western blot with 20017-1-AP (NCOR2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

20017-1-AP targets NCOR2 in WB, IF, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name nuclear receptor co-repressor 2
Calculated Molecular Weight 275 kDa
Observed Molecular Weight180 kDa
GenBank Accession NumberNM_006312
Gene Symbol NCOR2
Gene ID (NCBI) 9612
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

NCOR2, also named as CTG26, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC-1, TRAC1 and SMAP270, belongs to the N-CoR nuclear receptor corepressors family. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. The antibody recognizes all the isoforms of NCOR2. An about 180 KDa was also reported(PMID: 23081895).

Publications

SpeciesApplicationTitle
humanCoIP

Adv Sci (Weinh)

Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.

Authors - Shaliu Luo
View Article
humanWB

Cancer Sci

LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.

Authors - Yangjun Wu
View Article
IF

Front Pharmacol

Analysis of Effect of Schisandra in the Treatment of Myocardial Infarction Based on Three-Mode Gene Ontology Network.

Authors - Siyao Hu
View Article