NESP55,GNAS Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66253-1-Ig |CloneNo.: 1A9C10

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Con: 150 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
fetal human brain tissue, pig brain tissue

Positive IHC detected in:
human pancreas tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
GNAS complex locus

Calculated molecular weight:
45 kDa

Observed molecular weight:
46 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GNAS

Synonyms
AHO, C20orf45, dJ309F20.1.1, dJ806M20.3.3, GNAS, GNAS complex locus, GNAS1, GPSA, GSA, GSP, NESP, NESP55, NESP55,GNAS, PHP1A, PHP1B, POH, Protein ALEX
Background

Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The molecular weight of Gs(alpha) protein is about 46 kDa.


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