neuromedin B Polyclonal antibody

neuromedin B Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (2)

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 10888-1-AP

Synonyms

neuromedin B, NMB



Tested Applications

Positive IHC detected inmouse brain tissue, human brain tissue, human breast cancer tissue, human skin tissue, human stomach tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10888-1-AP targets neuromedin B in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, monkey, chimpanzee
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen neuromedin B fusion protein Ag0842
Full Name neuromedin B
Calculated Molecular Weight 16 kDa
GenBank Accession NumberBC007407
Gene Symbol NMB
Gene ID (NCBI) 4828
RRIDAB_10895967
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. It exerts its function via NMB receptor (NMB-R). NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in brain, gastrointestinal tract, pancreas, adrenals, and adipose tissue. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo.

Protocols

Product Specific Protocols
WB protocol for neuromedin B antibody 10888-1-APDownload protocol
IHC protocol for neuromedin B antibody 10888-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
chimpanzeeIHC

Brain Struct Funct

The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans.

Authors - Allman John M JM
humanIHC

Cancer Lett

Neuromedin B receptor antagonist suppresses tumor angiogenesis and tumor growth in vitro and in vivo.

Authors - Park Hyun-Joo HJ
human,monkeyWB

Am J Hum Biol

Biochemical specificity of von Economo neurons in hominoids.

Authors - Stimpson Cheryl D CD