RPH3AL Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 15297-1-AP

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Freight/Packing

Con: 24 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human liver tissue, L02 cells

Positive IP detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
rabphilin 3A-like (without C2 domains)

Calculated molecular weight:
34 kDa

Observed molecular weight:
38kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RPH3AL

Synonyms
No C2 domains protein, NOC2, Rab effector Noc2, Rabphilin 3A like protein, RPH3AL
Background

Rabphilin-3A-like (RPH3AL), also known as Noc2, is a Rab effector protein with a molecular weight of 38 kDa. It is expressed abundantly in endocrine cells but at low levels in exocrine tissues, playing a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells, and also having a key role in insulin secretion by pancreatic cells. RPH3AL functions as a potential RAB3B effector protein in epithelial cells, and RPH3AL gene is likely a tumor suppressor.


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