B23 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60096-2-Ig |CloneNo.: 9E3F12

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Tested Applications

Applications:
ELISA
Application not tested? Please see our Guarantee




Species specificity:
human

Recommended dilution:

Product Information


Source:
Mouse

Purification method:
Caprylic Acid/Ammonium Sulfate Precipitation

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Calculated molecular weight:
33 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NPM1

Synonyms
Background

Nucleophosmin (NPM1,B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.


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