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NPR3 Polyclonal antibody

NPR3 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 26706-1-AP

Synonyms

ANP C, ANPR C, ANPRC, GUCY2B, NPR3

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human kidney tissue using NPR3 Polyclonal antibody (26706-1-AP)

    IHC staining of human kidney using 26706-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 26706-1-AP (NPR3 Antibody) at dilution of 1:200 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human kidney tissue using NPR3 Polyclonal antibody (26706-1-AP)

    IHC staining of human kidney using 26706-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 26706-1-AP (NPR3 Antibody) at dilution of 1:200 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using NPR3 Polyclonal antibody (26706-1-AP)

    IHC staining of human liver cancer using 26706-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 26706-1-AP (NPR3 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using NPR3 Polyclonal antibody (26706-1-AP)

    IHC staining of human liver cancer using 26706-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 26706-1-AP (NPR3 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Tested Applications

Positive IHC detected inhuman kidney tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:100-1:400
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 26706-1-AP is NPR3 Fusion Protein expressed in E. coli.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NPR3 fusion protein Ag19071
Full Name natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
Calculated Molecular Weight 541 aa, 60 kDa
GenBank Accession NumberBC131540
Gene Symbol NPR3
Gene ID (NCBI) 4883
RRIDAB_2880607
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, is an atrial natriuretic peptide receptor. The family of natriuretic peptides elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. NPR3 has 3 isoforms with MWs of 37~60 kDa produced by alternative splicing, and may perform higher MW of 70 kDa with phosphorylation.

Protocols

Product Specific Protocols
IHC protocol for NPR3 antibody 26706-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC,IF

Sci Rep

A novel immune score model predicting the prognosis and immunotherapy response of breast cancer

Authors - Wenchang Lv
View Article