NR1H3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60134-1-Ig |CloneNo.: 4A4F7

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Freight/Packing

Con: 75 μg/150 μl

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Species specificity:
human, rat

Positive WB detected in:
MCF7 cells, HepG2 cells

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
nuclear receptor subfamily 1, group H, member 3

Calculated molecular weight:
50 kDa

Observed molecular weight:
50 kDa 44 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NR1H3

Synonyms
Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1
Background

NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.


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