Glucocorticoid receptor Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 11260-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Calculated molecular weight:
86 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NR3C1

Synonyms
NR3C1, Glucocorticoid receptor, GCCR, GR, GRL
Background

NR3C1 is a receptor for glucocorticoids, which owns a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. It is involved in cell proliferation and differentiation and specifically implicated in newborn birth weight, thus providing a biological mechanism by which NR3C1 expression may influence birth weight [PMID:22810058]. It also act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth [PMID:15037546].


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