OTUD7B Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66276-1-Ig |CloneNo.: 2C12D9

Featured Product KD/KO validated

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
OTU domain containing 7B

Calculated molecular weight:
427aa,48 kDa;843aa,93 kDa

Observed molecular weight:
92 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OTUD7B

Synonyms
CEZANNE, OTU domain containing 7B, OTUD7B, ZA20D1, Zinc finger protein Cezanne
Background

OUTD7B is a member of the A20 family of the deubiquitinating cysteine proteases, which has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. It plays a key role in the negative feedback regulation of NF-κB signaling in response to multiple stimuli and has been described as central gatekeeper in inflammation and immunity.


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