PAM Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 15464-1-AP

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Freight/Packing

Con: 36 μg/150 μl

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Tested Applications

Applications:
ELISA, WB
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
peptidylglycine alpha-amidating monooxygenase

Calculated molecular weight:
108 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PAM

Synonyms
PAL, PAM, Peptidylamidoglycolate lyase, PHM
Background

PAM(Peptidyl-glycine alpha-amidating monooxygenase) is a multifunctional protein containing 2 enzymes,PHM and PAL. The PAM protein containing the peptide encoded by exon A (Type B mRNA) is cleaved to form 41-and 43-kDa proteins,and the 75kDa PAM proteins is determined by lacking antigenic exon B(TypeA)(PMID:1740449).The substrate specificity of PAM is broad, and production of all a-amidated peptides may be dependent upon proteins encoded by the single copy PAM gene(PMID:8436961).It has 6 isoforms produced by alternative splicing.


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