PI3K p85(alpha) Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 11748-1-AP

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Freight/Packing

Con: 0 μg/150 μl

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Tested Applications

Applications:
ELISA, WB, IHC
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Calculated molecular weight:
85 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PIK3R1

Synonyms
GRB1, p85, p85 ALPHA, PI 3 Kinase p85 alpha, PI 3-kinase p85α, PI3 kinase subunit p85 alpha, PI3K p85(alpha), PI3K regulatory subunit alpha, PIK3R1
Background

Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.


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