Plasminogen Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17462-1-AP

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human blood tissue, human placenta tissue

Recommended dilution:
WB : 1:1000-1:4000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
plasminogen

Calculated molecular weight:
810aa,91 kDa

Observed molecular weight:
97 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PLG

Synonyms
Angiostatin, DKFZp779M0222, plasminogen, PLG
Background

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.


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