PPP1CB-Specific Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 10140-2-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, NIH/3T3

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
NIH/3T3 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein phosphatase 1, catalytic subunit, beta isoform

Calculated molecular weight:
37 kDa

Observed molecular weight:
37 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PPP1CB

Synonyms
PP1 Beta, PP 1B, PPP1CB, PPP1CD
Background

Protein phosphatase 1 (PP1) is the main eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular processes including protein-protein interactions, gene transcription, cell-cycle progression and apoptosis. It is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. The catalytic subunit of PP1 (PP1c) can interact with amount of regulatory subunits in vivo that target it to particular subcellular locations and regulate its activity towards specific substrates. PPP1CB migrated as a 37kd protein on SDS page. This antibody is specific to PPP1CB.


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