PRDX1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20568-1-AP

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Con: 72 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells

Positive IF detected in:
HepG2 cells, Hela cells

Recommended dilution:
WB : 1:1000-1:4000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
peroxiredoxin 1

Calculated molecular weight:
22 kDa

Observed molecular weight:
23 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRDX1

Synonyms
MSP23, NKEF A, NKEFA, PAG, PAGA, PAGB, peroxiredoxin 1, PRDX1, PRX1, PRXI, TDPX2, Thioredoxin peroxidase 2
Background

PRDX1, also named as PAGA, PAGB, TDPX2, PAG and NKEF-A, belongs to the ahpC/TSA family. It is involved in redox regulation of the cell. PRDX1 reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. PRDX1 plays an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. The antibody is specific to PRDX1.


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