PRDX4 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60286-1-Ig |CloneNo.: 5B6F1

Featured Product KD/KO validated

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Con: 109 μg/150 μl

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Species specificity:
human

Positive WB detected in:
K-562 cells, HepG2

Positive IHC detected in:
human colon tissue, human colon tissue, human pancreas cancer tissue, human prostate cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
peroxiredoxin 4

Calculated molecular weight:
31 kDa

Observed molecular weight:
31 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRDX4

Synonyms
Antioxidant enzyme AOE372, AOE37 2, peroxiredoxin 4, Peroxiredoxin IV, PRDX4, PRX 4, Prx IV, Thioredoxin peroxidase AO372
Background

PRDX4(Peroxiredoxin-4) is also named as AOE37-2, Prx-IV and belongs to the AhpC/TSA family. PRDX4 is associated with acrosome formation during rat spermatogenesis and has a protective role in the male reproductive tract, because the phenotype of mice lacking this isoform includes testicular atrophy and increased sperm DNA damage(PMID:20864641). It is initially synthesized as a membrane-binding 31-kDa protein and processed into a 27-kDa secretory form and is discarded with the residual bodies(PMID:19208552). PRDX4 is a pentamer of dimers(PMID:23025503).


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