AMPK alpha 2 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 18167-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 29 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human skeletal muscle tissue, HeLa cells, MCF-7 cells, rat ovary tissue, SKOV-3 cells

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human pancreas tissue, human skeletal muscle tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein kinase, AMP-activated, alpha 2 catalytic subunit

Calculated molecular weight:
552aa,62 kDa

Observed molecular weight:
62 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRKAA2

Synonyms
AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, PRKAA, PRKAA2
Background

PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).


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