PTPRO Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 12161-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Tested Applications

Applications:
ELISA, IHC, WB
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein tyrosine phosphatase, receptor type, O

Calculated molecular weight:
138 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PTPRO

Synonyms
GLEPP1, PTP U2, PTPase U2, PTPRO, PTPU2, R PTP O
Background

PTPRO(receptor-type tyrosine-protein phosphatase O) is also named as GLEPP1, PTPU2 and belongs to the protein-tyrosine phosphatase family. The protein is a receptor-like membrane protein tyrosine phosphatase expressed at the apical membrane of the podocyte foot processes in the kidney(PMID:21722858). The 1,159-amino acid predicted mature protein contains a large extracellular domain, a single transmembrane domain, and a single intracellular PTPase domain. Defects in PTPRO are the cause of nephrotic syndrome type 6 (NPHS6). It has 4 isoforms produced by alternative splicing and several glycosylation sites.


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