Rab18 Monoclonal antibody

Rab18 Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse and More (1)

Applications

WB, IF,ELISA

Conjugate

Unconjugated

CloneNo.

4D5B8

Cat no : 60057-1-Ig

Synonyms

RAB18, RAB18LI1, Ras related protein Rab 18



Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

60057-1-Ig targets Rab18 in WB, IF,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivitymouse, monkey
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Rab18 fusion protein Ag1841
Full Name RAB18, member RAS oncogene family
Calculated Molecular Weight 206 aa, 23 kDa
GenBank Accession NumberBC015014
Gene Symbol RAB18
Gene ID (NCBI) 22931
Conjugate Unconjugated
Form Liquid
Purification MethodCaprylic acid/ammonium sulfate precipitation
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

RAB18 is a member of a family of Ras-related small GTPases. RAB18 plays a role in apical endocytosis/recycling, and may be implicated in transport between the plasma membrane and early endosomes. It also plays a key role in eye and brain development and neurodegeneration. Defects in RAB18 are associated with Warburg micro syndrome type 3.

Protocols

Product Specific Protocols
IF protocol for Rab18 antibody 60057-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
monkeyWB

J Cell Biol

Rab18 and a Rab18 GEF complex are required for normal ER structure.

Authors - Andreas Gerondopoulos
mouseIF

Redox Biol

Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner.

Authors - Yu Yan
mouseIF

J Cell Biol

Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions.

Authors - Dijin Xu
mouseWB

Mol Neurobiol

Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.

Authors - Fang-Shin Nian