RAC2 Antibody 5 Publications

Mouse Monoclonal| Catalog number: 60077-1-Ig |CloneNo.: 4C2H6

Featured Product KD/KO validated

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Freight/Packing

Con: 225 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HL60 cells, HL-60 cells

Positive IHC detected in:
human spleen tissue, human spleen tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

Calculated molecular weight:
21 kDa

Observed molecular weight:
21 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RAC2

Synonyms
EN 7, Gx, HSPC022, p21 Rac2, RAC2, Small G protein
Background

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.


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