RCAS1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66170-1-Ig |CloneNo.: 4H8A12

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Freight/Packing

Con: 101 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HEK-293 cells

Positive IHC detected in:
human lung cancer tissue, human breast cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
estrogen receptor binding site associated, antigen, 9

Calculated molecular weight:
213aa,24 kDa

Observed molecular weight:
30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EBAG9

Synonyms
EB9, EBAG9, PDAF, RCAS1
Background

Estrogen receptor–binding fragment-associated antigen 9 (EBAG9) gene was identified as an estrogen-responsive gene. The gene product, receptor-binding cancer antigen expressed on SiSo cells (RCAS1), is associated with aggressive characteristics and poor overall survival for 15 different human malignancies. The correlation between RCAS1 expression and several clinicopathological variables, including tumor size, clinical stage, invasion depth and lymph node metastasis highlights this molecule's clinical significance. Expression of RCAS1 in tumor cells plays an important role in evasion from host immune system resulting tumor progression, invasion and metastasis. Further exploration of RCAS1 biological function will facilitate development of novel therapeutic strategies that target RCAS1.


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