RCC1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22142-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 57 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, monkey

Positive WB detected in:
HeLa cells,HepG2 cells, Jurkat cells, HEK-293 cells, A431 cells, NIH/3T3 cells, COS-7 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human testis tissue, human small intestine tissue, human testis tissue

Positive IF detected in:
A431 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
regulator of chromosome condensation 1

Calculated molecular weight:
421aa,45 kDa

Observed molecular weight:
45-50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RCC1

Synonyms
Cell cycle regulatory protein, CHC1, RCC1, RCC1 I
Background

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.


Back
to top