RIPK1-Specific Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 17519-1-AP

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
NIH/3T3 cells, HeLa cells, K-562 cells, rat liver tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human heart tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
receptor (TNFRSF)-interacting serine-threonine kinase 1

Calculated molecular weight:
76 kDa

Observed molecular weight:
74 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RIPK1

Synonyms
Cell death protein RIP, FLJ39204, Receptor interacting protein 1, RIP, RIP 1, RIP1, RIPK1
Background

RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).


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