RPL11 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 16277-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 31 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
human liver tissue, BxPC-3 cells, mouse lung tissue, mouse pancreas tissue, rat liver tissue

Positive IF detected in:
BxPC-3 cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ribosomal protein L11

Calculated molecular weight:
177aa,20 kDa

Observed molecular weight:
20kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RPL11

Synonyms
60S ribosomal protein L11, CLL associated antigen KW 12, DBA7, GIG34, ribosomal protein L11, RPL11
Background

Ribosomal protein L11 is one of 80 mammalian ribosome proteins. It can bind to 5S ribosomal RNA, for it's required for rRNA maturation and formation of the 60S ribosomal subunit. It can inhibite 40S or 60S ribosome biogenesis via mediated p53 induction. Once retained by PICT1 in the nucleolus, RPL11 involve in regulation of the MDM2-P53 pathway and promotion of tumor progression.


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