RRM1-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19686-1-AP

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A549 cells, HEK-293 cells, HeLa cells

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
ribonucleotide reductase M1

Calculated molecular weight:
90 kDa

Observed molecular weight:
80-90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RRM1

Synonyms
R1, ribonucleotide reductase M1, RIR1, RR1, RRM1
Background

RRM1, also named as RR1, belongs to the ribonucleoside diphosphate reductase large chain family. RRM1 provides the precursors necessary for DNA synthesis. RRM1 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.RRM1 is a key enzyme in DNA synthesis: low level expression of RRM1 is associated with poor survival. RRM1 is a prognostic marker of NSCLC. The antibody is specfic to RRM1.


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