DLG1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 55085-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse lung tissue, HeLa cells

Positive IHC detected in:
human heart tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
discs, large homolog 1 (Drosophila)

Calculated molecular weight:
100 kDa

Observed molecular weight:
120 kDa or 130-140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DLG1

Synonyms
Disks large homolog 1, dJ1061C18.1.1, DKFZp761P0818, DKFZp781B0426, DLG1, DLGH1, hdlg, SAP 97, SAP97, Synapse associated protein 97
Background

DLG1, also naemd as SAP97, hDlg and DLGH1, belongs to the MAGUK family. It is essential multidomain scaffolding protein required for normal development. DLG1 may play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. It regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. DLG1 is a functional regulator of Kv1.5 channel. The DLG1-MPP7 complex promotes epithelial cell polarity and tight junction formation. The antibody is specific to DLG1.


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