OXCT1 Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 12175-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, human heart tissue, human kidney tissue, human lung tissue, mouse skeletal muscle tissue, mouse thymus tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human gliomas tissue, human gliomas tissue, human medulloblastoma tissue, human prostate cancer tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
3-oxoacid CoA transferase 1

Calculated molecular weight:
520aa,56 kDa

Observed molecular weight:
56 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OXCT1

Synonyms
3 oxoacid CoA transferase 1, OXCT, OXCT1, SCOT, SCOT s
Background

3-oxoacid-CoA transferase 1 (OXCT1), encoded by nuclear gene, is a mitochondrial CoA transferase required for ketone body degradation. It catalyzes the transfer of CoA from succinyl-CoA to acetoacetate, generating acetoacetyl-CoA. OXCT1 is expressed in brain, heart, and skeletal muscle, but not in liver. This antibody specifically recognizes endogenous OXCT1. (21209089)


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