SEC5/EXOC2 Antibody 3 Publications

Mouse Monoclonal| Catalog number: 66011-1-Ig |CloneNo.: 1C11G2

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Freight/Packing

Con: 183 μg/150 μl

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Species specificity:
human, mouse, pig, rat

Positive WB detected in:
mouse brain tissue, human brain tissue, pig brain tissue, rat brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human breast cancer tissue, human liver cancer tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:2500-1:10000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:200-1:800
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
exocyst complex component 2

Calculated molecular weight:
924aa,104 kDa

Observed molecular weight:
100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EXOC2

Synonyms
EXOC2, exocyst complex component 2, Exocyst complex component Sec5, FLJ11026, SEC5, SEC5L1, Sec5p
Background

EXOC2 (exocyst complex component 2), also known as SEC5 and SEC5L1, is a component of the exocyst complex, and is required to mediate RalB-dependent survival signals in transformed cells. The exocyst complex, composed of eight evolutionarily conserved subunits (SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70, and EXO84), is involved in tethering post-Golgi secretory vesicles to specific plasma membrane domains. The gene of EXOC2 maps to chromosome 6p25.3, and encodes a 924-amino acid protein with an experimentally determined molecular mass of 95-100 kDa. EXOC2 mRNA is widely expressed with highest levels in brain and placenta.


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