SESN1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 21668-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 50 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
human skeletal muscle tissue, human testis tissue, mouse liver tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
sestrin 1

Calculated molecular weight:
551aa,64 kDa

Observed molecular weight:
66-68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SESN1

Synonyms
p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1
Background

Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 1 is implicated in the inhibition of cell growth. It is approximately a 66kDa protein in humans (551 amino acids).


Back
to top