SHMT1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 14149-1-AP

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Freight/Packing

Con: 36 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human kidney tissue, HeLa cells, HepG2 cells, human liver tissue, mouse kidney tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
serine hydroxymethyltransferase 1 (soluble)

Calculated molecular weight:
483aa,53 kDa

Observed molecular weight:
53 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SHMT1

Synonyms
CSHMT, Serine methylase, SHMT, SHMT1
Background

SHMT1 is the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. This antibody can detect both 49kd and 53 kd isoforms in western blotting.


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