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  • KD/KO Validated

SOX13 Polyclonal antibody

SOX13 Polyclonal Antibody for IF, IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IP, IHC, IF, chIP, ELISA

Conjugate

Unconjugated

Cat no : 18902-1-AP

Synonyms

ICA12, Islet cell antigen 12, Sox 13, SOX13, Transcription factor SOX 13



Tested Applications

Positive WB detected inBGC-823 cells, NCI-H1299 cells
Positive IP detected inSH-SY5Y cells
Positive IF detected inHela cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)IF : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

18902-1-AP targets SOX13 in WB, IP, IHC, IF, chIP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SOX13 fusion protein Ag13537
Full Name SRY (sex determining region Y)-box 13
Calculated Molecular Weight 622 aa, 69 kDa
Observed Molecular Weight 69 kDa
GenBank Accession NumberBC106038
Gene Symbol SOX13
Gene ID (NCBI) 9580
RRIDAB_10642149
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SRY-BOX 13(SOX13), identified a sequence homologous more than 60% to the SRY HMG box ,with a centrally located HMG box and an N-terminal leucine zipper motif with a neighboring glutamine stretch called a Q box. SOX13 binds to the consensus HMG-box motif. It's an IDDM-specific human autoantigen, and a gamma-delta-specific gene in the immune system. It can modulates Wnt/TCF activity. This is a rabbit polyclonal raised against part of N-terminal chain of SOX13 of human origin.

Protocols

Product Specific Protocols
WB protocol for SOX13 antibody 18902-1-APDownload protocol
IF protocol for SOX13 antibody 18902-1-APDownload protocol
IP protocol for SOX13 antibody 18902-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IF

Front Cardiovasc Med

Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells

Authors - Catherine Demos
  • KD Validated
humanWB,IHC

Lab Invest

Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.

Authors - Min Feng
  • KD Validated
mouseWB, IF

Mol Cell Biochem

Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.

Authors - Mikella Daigle
humanWB,IHC

Bioengineered

Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.

Authors - Xiaoyan Jin
  • KD Validated
humanWB,chIP

J Exp Clin Cancer Res

FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma.

Authors - Zhenwei He