SPHK1-Phospho-Ser225 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 19561-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 49 μg/150 μl

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Species specificity:
human

Positive WB detected in:
L02 cells, human testis tissue, L02 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
sphingosine kinase 1

Calculated molecular weight:
51 kDa

Observed molecular weight:
45-47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SPHK1

Synonyms
SK 1, sphingosine kinase 1, SPHK, SPHK1 phopho, SPHK1-Phospho-Ser225, SPK, SPK 1
Background

SPHK1, also named as SPHK and SPK, catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. SPHK1 acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The antibody is specific to Ser(311)-phospho of SPHK1(isoform2) or Ser(225)-phospho of SPHK1(isoform1).


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